Indications of Daclin 25 ml Lotion

Clindamycin lotion is indicated for the treatment of acne. Other uses for clindamycin lotion are as follows:

Skin infections such as erythema due to Corynebacterium minutissimum; rosacea, perioral dermatitis, folliculitis, fluid retention, chronic lymphedema, and familial pemphigus.

Pharmacology of Daclin 25 ml Lotion

Clindamycin is a lincosamide antibiotic used to treat infections caused by susceptible microorganisms. Clindamycin is a semi-synthetic antibiotic derived from lincomycin. It has anti-acne and antibacterial activity. It binds to subunit 50 of the bacterial ribosome and inhibits the early stages of protein synthesis. It is very strong against gram-positive and anaerobic bacteria.

Microbiology: Aerobic gram-positive cocci, including: Staphylococcus aureus, Staphylococcus epidermidis (penicillinase-producing and non-penicillinase-producing strains), streptococcus, pneumococcus. Gram-negative anaerobic bacilli, including: Bacteroides species, Fusobacterium species. Gram-positive, non-spore forming anaerobic bacilli, including: Propionibacterium species, Eubacterium species, Actinomyces species. Anaerobic cocci and Gram-positive bacteria, including: Peptococcus species, Peptostreptococcus species, Microaerophilic streptococci, C. perfringes

Dosage & Administration of Daclin 25 ml Lotion

At first, wash the face or affected area gently with warm water or soap. When the skin is completely dried (about 30 minutes later) apply a thin film of Clindamycin lotion to the entire affected area twice daily. The Applied area should not be washed within 3 hours. Noticeable improvement is usually seen after about 6 weeks. However, 8 to 12 weeks of treatment may be required for maximum benefit. Eye, lip or nose contact should be avoided while applying Clindamycin lotion.

Interaction of Daclin 25 ml Lotion

Clindamycin enhances the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Due to the possible clinical implications, these two drugs should not be administered simultaneously.

Side Effects of Daclin 25 ml Lotion

If you are taking a prescription monoamine oxidase inhibitor (MAOI) now (certain medicines for depression, mental or emotional illness, or Parkinson’s disease) or for two weeks after stopping an MAOI. If you are not sure if your prescription medicine contains a MAOI, talk to your doctor or pharmacist before taking this product.

Pregnancy & Lactation

There are no adequate data for safe use during pregnancy. Animal studies have shown no adverse effects on the fetus. It is not known whether clindamycin is excreted in human milk after topical administration. However, clindamycin lotion can be used with caution while breastfeeding.

Precautions & Warnings

Clindamycin lotion is not for oral, ophthalmic, or vaginal use. Avoid exposure to sunlight and spotlights. Apply sunscreen every day.

Therapeutic Class

Macrolides

Storage Conditions

Store the tube below 25 °C, away from light & moisture. Keep out of the reach of children.

Pharmaceutical Name of Daclin 25 ml Lotion

ACI Limited

Generic of Daclin 25 ml Lotion

Clindamycin