Indications of Cozopt 5 ml

This Eye Drops is used to treat high intraocular pressure in those who have open angle glaucoma or ocular hypertension and aren’t responding well to topical beta blockers.

Pharmaceutical Name of Cozopt 5 ml

Aristopharma Ltd.

Pharmacology

Dorzolamide, a carbonic anhydrase inhibitor, is similar to acetazolamide in its activities. Dorzolamide reduces aqueous humor secretion by inhibiting carbonic anhydrase in the ciliary processes of the eye. When used jointly, there is a greater reduction in intraocular pressure than when either component is used alone, but not as much as when dorzolamide and timolol are given at the same time.

Timolol maleate, a nonselective -adrenergic blocker, inhibits the development of aqueous humor.

Dosage & Administration

Instill one drop in the conjunctival sac of the affected eye(s) twice daily.

Interaction of Cozopt 5 ml

Oral calcium channel blockers, catecholamine-depleting medicines or -blockers, antiarrhythmics (e.g. amiodarone), digitalis glycosides, parasympathomimetics, opioids, and MAOIs cause additive hypotension and bradycardia. Oral carbonic anhydrase or -blockers have additive systemic adverse effects; avoid using them together. CYP2D6 inhibitors (e.g. quinidine, SSRIs) and timolol in combination for systemic -blockade.

Contraindications

Contraindicated in patients who are hypersensitive to any of the components of this preparation.

Side Effects of Cozopt 5 ml

Mild burning, ocular hyperemia, and impaired vision are all possible side effects.

Pregnancy & Lactation

Pregnancy: No suitable and well-controlled trials have been conducted in pregnant women. During pregnancy, these Eye Drops should only be used if the potential benefit outweighs the potential risk to the fetus.

When administering This Eye Drops to a breastfeeding mother, extreme caution should be observed.

Precautions & Warnings

Only for ophthalmic use. Patients should remove their contact lenses before using this preparation and wait 15 minutes before putting them back in.

Therapeutic Class

Drugs for miotics and glaucoma

Storage Conditions

Store between 15-30°C. Protect from light.

Generic of Cozopt 5 ml

Dorzolamide + Timolol