Generic

Olopatadine Hydrochloride

Indications

Olopatadine is indicated for the treatment of ocular itching associated with allergic conjunctivitis.

Pharmacology

Olopatadine is an inhibitor of the release of histamine from the mast cell and a relatively selective histamine H1‐antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells. Olopatadine is devoid of effects on alpha adrenergic, dopamine and muscarinic type 1 and 2 receptors. Following topical ocular administration in human, olopatadine was shown to have low systemic exposure.

Dosage & Administration

• 1% Sterile Eye Drops: One drop in each affected eye two times per day at an interval of 6 to 8 hours.
• 2% Sterile Eye Drops: One drop in the affected eye once a day.
• 7% Sterile Eye Drops: One drop in each affected eye once a day.

Interaction

May result in additive CNS depression with CNS depressants.

Contraindications

Olopatadine Hydrochloride ophthalmic solution is contraindicated in persons with a known hypersensitivity to Olopatadine Hydrochloride.

Side Effects

Migraines have been detailed at an rate of 7%. The taking after antagonistic encounters have been detailed in less than 5% of patients: Asthenia, obscured vision, burning or stinging, cold disorder, dry eye, outside body sensation, hyperemia, touchiness, keratitis, cover edema, sickness, pharyngitis, pruritus, rhinitis, sinusitis, and taste depravity

Pregnancy & Lactation

There are no satisfactory and well controlled ponders in pregnant ladies. Since creature considers are not continuously prescient of human reactions, this medicate ought to be utilized in pregnant ladies as it were in the event that the potential advantage to the mother legitimizes the potential chance to the fetus.

It isn’t known whether topical visual organization might result in adequate systemic assimilation to produce detectable amounts within the human breast drain. By the by, caution ought to be worked out when Olopatadine Hydrochloride ophthalmic arrangement is managed to a nursing mother.

Precautions & Warnings

Olopatadine HCl ophthalmic arrangement ought to not be utilized to treat contact focal point related aggravation. Patients who wear delicate contact focal points ought to be teaching to hold up at slightest ten minutes after ingrains Olopatadine Hydrochloride ophthalmic arrangement some time recently they embed their contact focal points.

Therapeutic Class

Ophthalmic Non-Steroid drugs

Storage Conditions

Store below 30° C in a cool and dry place protected from light. Keep out of reach of children. Do not touch the dropper tip to surfaces since this may contaminate the solution. Do not use after 30 days of first opening.

Pharmaceutical Name

ACI Limited