Cerox Cv 500 MG+125 MG


Cerox Cv 500 MG+125 MG


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Indications of Cerox CV 500 Tablet

It is shown for the treatment of contaminations caused by delicate bacteria.

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes.
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase creating strains) or Streptococcus pyogenes.
  • Intense bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase creating strains)
  • Lower respiratory tract diseases counting pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (counting beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
  • Acute bacterial worsening of persistent bronchitis and auxiliary bacterial diseases of Intense bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains).
  • Uncomplicated skin and skin-structure contaminations caused by Staphylococcus aureus (counting beta-lactamase creating strains) or Streptococcus pyogenes.
  •  Uncomplicated urinary tract diseases caused by E.coli or Klebsiella pneumoniae.
  • Bone and Joint Contaminations caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains).
  • Uncomplicated Gonorrhea caused by penicillinase-producing and non-penicillinase creating strains of Neisseria gonorrhoeae.
  • Early Lyme Malady (erythema migrans) caused by Borrelia burgdorferi.
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (counting ampicillin-resistant strains) & Klebsiella spp.
  • Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (counting ampicillin-resistant strains), Neisseria meningitidis & Staphylococcus aureus (penicillinase and non-penicillinase creating strains)
  • Switch treatment (Injectable to verbal)


Pharmacology of Cerox CV 500 Tablet

Cefuroxime may be a bactericidal moment era cephalosporin anti-microbial which is dynamic against a wide extend of Gram-positive and Gram-negative helpless life forms counting numerous beta-lactamase creating strains. Cefuroxime represses bacterial cell divider union by interferometer with the transpeptidation handle.

Clavulanic corrosive may be a actually inferred beta lactamase inhibitor created by Streptomyces clavuligerus. It has comparative structure to beta lactam anti-microbials which ties irreversibly to beta-lactamase chemicals and inactivates them. Clavulanic corrosive gives assurance of Cefuroxime from corruption by beta lactamase chemicals and gives a arrangement for the treatment of bacterial contaminations caused by beta lactam safe microscopic organisms.


Dosage  and Administration of Cerox CV 500 Tablet

Adolescents and grown-ups (13 a long time and older)-

  • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
  • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
  • Acute bacterial compounding of constant bronchitis: 250-500 mg b.i.d. for 10 days
  • Secondary bacterial contaminations of intense bronchitis: 250-500 mg b.i.d. for 5-10 days
  •  Uncomplicated skin and skin structure contaminations: 250-500 mg b.i.d. for 10 days
  • Uncomplicated urinary tract contaminations: 250 mg b.i.d. for 7-10 days
  • Uncomplicated Gonorrhea: 1000 mg b.i.d. Single dose Community procured pneumonia: 250-500 mg b.i.d. for 5-10 days
  • MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
  • Early Lyme malady: 500 mg b.i.d. for 20 days

Pediatric Patients (3 months to 12 years)-

  • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
  • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
  • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
  • Impetigo: 30 mg/kg/day b.i.d for 10 days

Cefuroxime-Clavulanic Corrosive tablet may be taken without respect of nourishment.


Interaction of Cerox CV 500 Tablet

Concomitant organization of probenecid with Cefuroxime-Clavulanic Corrosive increments the range beneath the serum concentration versus time bend by 50%. Medicate that decreases gastric corrosiveness may result in a lower bioavailability of Cefuroxime and tend to cancel the impact of postprandial retention.


Cefuroxime-Clavulanic Corrosive is contraindicated in patients with known sensitivity to cephalosporin & in patients with Pseudomembranous Colitis.


Side Effects of Cerox CV 500 Tablet

Generally Cefuroxime-Clavulanic Corrosive is well endured. Be that as it may, a number of side impacts like sickness, spewing, the runs, stomach distress or torment may happen. As with other broad-spectrum anti-microbials, drawn out organization of Cefuroxime and Clavulanic corrosive combination may result in excess of nonsusceptible microorganisms. Seldom (<0.2%) renal brokenness, anaphylaxis, angioedema, pruritis, hasty and serum ailment like urticaria may show up.


Pregnancy & Lactation

Whereas all anti-microbials ought to be maintained a strategic distance from within the to begin with trimester on the off chance that conceivable. Be that as it may, Cefuroxime-Clavulanic Corrosive can be securely utilized in afterward pregnancy to treat urinary and other diseases. Cefuroxime-Clavulanic Corrosive is excreted into the breast drain in little amounts. In any case, the plausibility of sensitizing the newborn child ought to be kept in intellect.


Precautions & Warnings

Cefuroxime ought to be given with care to patients accepting concurrent treatment with powerful diuretics & who has history of colitis.


Therapeutic Class

Second generation Cephalosporins


Storage Conditions

Store in a cool, dry put (underneath 30o C), absent from light and dampness. Keep out of the reach of children.


Pharmaceutical Name of Cerox CV 500 Tablet

ACI Limited


Generic of Cerox CV 500 Tablet

Cefuroxime Axetil + Clavulanic Acid