Indications of Cefotil 70 ml

It’s used to treat infections caused by bacteria that are susceptible to antibiotics.

• Streptococcus pyogenes causes pharyngitis and tonsillitis.
• Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase generating strains), or Streptococcus pyogenes cause acute bacterial otitis media.
• Streptococcus pneumoniae or Haemophilus influenzae induce acute bacterial maxillary sinusitis (non-beta-lactamase-producing strains)
• Lower respiratory tract infections including pneumonia, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta-lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
• Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains), or Haemophilus parainfluenzae cause acute bacterial aggravation of chronic bronchitis and secondary bacterial infections of acute bronchitis (beta-lactamase negative strains).
• Skin and skin structure infections caused by Staphylococcus aureus (including beta-lactamase generating strains) or Streptococcus pyogenes.
• coli or Klebsiella pneumoniae infections of the urinary tract.
• Staphylococcus aureus infections of the bones and joints (penicillinase- and non-penicillinase-producing strains).
• Penicillinase-producing and non-penicillinase-producing strains of Neisseria gonorrhoeae cause gonorrhea.
• Borrelia burgdorferi causes early Lyme Disease (erythema migrans).

Pharmaceutical Name of Cefotil 70 ml

Square Pharmaceuticals Ltd.

Pharmacology

Cefuroxime is a well-studied and efficient antibacterial drug with a broad-spectrum bactericidal action against a variety of infections, including those that produce -lactamases. Cefuroxime is resistant to bacterial-lactamase and hence efficacious against a wide range of ampicillin- and amoxicillin-resistant strains.

Dosage & Administration of Cefotil 70 ml

Tablet or Suspension-

Adolescents and adults (13 years and older)-

• Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
• Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
• Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
• Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
• Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
• Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
• Uncomplicated Gonorrhoea: 1000 mg Single dose
• Community-acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
• MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
• Early Lyme disease: 500 mg b.i.d. for 20 days

Paediatric Patients (3 months to 12 years)-

• Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
• Acute otitis media: 30 mg/kg/day b.i.d for 10 days
• Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
• Impetigo: 30 mg/kg/day b.i.d for 10 days

Contraindications

Cefuroxime is not recommended for people who have a Cephalosporin allergy.

Side Effects of Cefotil 70 ml

Cefuroxime has been linked to a small number of side effects, all of which have been moderate and transitory. Rashes and stomach issues have been mentioned as side effects. Prolonged usage of antibiotics, like other medications, can lead to the proliferation of non-susceptible organisms, such as bacteria, and Candida.

Pregnancy & Lactation

Cefuroxime is classified as a pregnancy category B by the US Food and Drug Administration. However, no appropriate and well-controlled trials in pregnant women have been conducted. Because animal reproduction studies do not always anticipate a human response, this medication should only be taken during pregnancy if absolutely necessary. Human milk has been found to contain cefuroxime. When Cefuroxime is given to a nursing mother, care should be used.

Precautions & Warnings

Cefuroxime should be used with caution in individuals who are taking strong diuretics and have a history of colitis. Although there have been reports of cross-reactions, cephalosporin medicines may often be given safely to individuals who are hypersensitive to penicillin. Cefuroxime has demonstrated that at the recommended dosage levels, this is unlikely to be an issue.

Therapeutic Class

Cephalosporins of the second generation

Storage Conditions

Store in a cool, dry place (below 30o C), away from light & moisture. Keep out of the reach of children.

Generic of Cefotil 70 ml

Cefuroxime Axetil