Cartilex D 750 MG+50 MG


Cartilex D 750 MG+50 MG


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Glucosamine Sulfate + Diacerein



Osteoarthritis, rheumatoid arthritis, and bone and joint injuries are among the conditions for which this medication is prescribed.



Glucosamine (2-amino-2-deoxy-alpha-D-glucose) is a naturally occurring amino sugar that is created by the body and found in a variety of meals. It’s the most basic building component for glycosaminoglycans (GAGs) like Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate production. GAGs bond to proteins to create proteoglycans, which are an important component of articular cartilage. Osteoarthritis develops when cartilage in a joint deteriorates. It also aids in the formation of ligaments, tendons, nails, and other connective tissues. When we take a supplement containing artificially generated Glucosamine Sulfate, our body’s Glucosamine levels rise, making cartilage formation and repair easier. Glucosamine also stimulates cartilage chondrocytes, which aid in the production of GAGs.

In humans, approximately 90% of glucosamine sulfate delivered as an oral dose is absorbed through the digestive tract. The liver is the primary metabolizer, and it is eliminated primarily through urine.

Diacerein is a drug that is used to treat osteoarthritis. It also possesses anti-inflammatory, antipyretic, and analgesic properties. It reduces the production of InterLeukin-1 (IL-1), the major cytokine involved in cartilage breakdown, in vitro. It has been proven to have a disease-modifying impact in laboratory models of osteoarthritis and in human subjects with finger joint and knee osteoarthritis due to its particular mode of action.

Diacerein has a 56 percent oral bioavailability. Concurrent food consumption prolongs the duration to peak concentration while increasing absorption by 25%. As a result, diacerein should be taken with food. Binds mostly to protein albumin. Following oral administration, diacerein is metabolized substantially (100%) in the liver. The amount of diacerein excreted in the urine in the form of its metabolites has varied between 35 and 60%.


Dosage & Administration

Use in adults: One tablet twice daily with food.

Use in children and adolescents
: The safety and effectiveness of children and adolescents under the age of 18 years have not been established.



No significant drug interaction of Glucosamine and Chondroitin was reported with antibiotics, antihypertensives, nitrates, antiarrhythmics, anxiolytics, hypoglycemic agents, or anti-secretives.



There are no contraindications for Glucosamine and Chondroitin. But proven hypersensitivity to these ingredients should be considered.

Side effects: Safety studies with Glucosamine and Chondroitin show no demonstrable toxicity. Rarely occurring side effects like mild and reversible intestinal flatulence are almost like a placebo.


Side Effects

There have been no major side effects reported. Nausea, vomiting, diarrhea, epigastric discomfort, headache, skin rashes, and a bright yellow urine hue are all possible side effects.


Pregnancy & Lactation

Women who are pregnant or who could become pregnant should not supplement with Glucosamine and Chondroitin. These ingredients have not been studied enough to determine their effects on a developing fetus and no studies have evaluated the use of this combination during pregnancy or lactation. It should be taken with caution and medical advice during pregnancy and lactation.


Precautions & Warnings

Diabetic patients are advised to monitor blood glucose levels regularly while taking Glucosamine. No special studies were formed in patients with renal and/or hepatic insufficiency. The toxicological and pharmacokinetic profile of the product does not indicate limitations for these patients. However, administration to these patients with severe hepatic or renal insufficiency should be under appropriate medical supervision.


Therapeutic Class

Cartilage Formation Stimulation


Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children’s reach.


Pharmaceutical Name

ACI Limited