Indications of Betaderm 15 Ointment

Betamethasone Valerate cream or ointment is indicated for the treatment of-

▪ Eczema in children and adults including atopic

▪ Infantile and discoid eczema

▪ Prurigo nodularis

▪ Psoriasis (excluding widespread plaque psoriasis)

▪ Neurodermatoses including lichen simplex and lichen planus

▪ Seborrheic dermatitis

▪ Contact sensitivity reaction

▪ Discoid lupus erythematosus and may be used as an adjunct to systemic steroid therapy in generalized erythroderma.

Pharmacology of Betaderm 15 Ointment

Betamethasone valerate is a potent topical corticosteroid. Topical corticosteroids have anti-inflammatory, antipruritic, and vasoconstrictive actions when administered. Betamethasone acts by inhibiting of phospholipase A2 activity and reduces the formation of prostaglandins and leukotrienes in local tissues.

Dosage & Administration of Betaderm 15 Ointment

Apply sparingly to the affected area two or three times daily until improvement occurs, then twice daily or less. The usual maximum duration of therapy is three weeks.

Interaction of Betaderm 15 Ointment

There are no critical medication intelligent detailed with Betamethasone Cream/Ointment.

Contraindications

Betamethasone Valerate cream or ointment is contraindicated in the following conditions :

▪ Hypersensitivity to any of the ingredients in the preparation.

▪ Rosaceae & acne vulgaris.

▪ Perioral dermatitis, perianal &

genital pruritis.

▪ Viral infections of the skin, e.g. herpes simplex & chicken pox.

▪ Primary infected skin lesions caused by fungi or bacteria.

▪ Dermatoses in children under one year of age.

Side Effects of Betaderm 15 Ointment

The following local adverse reactions are more common with the use of high doses, long-term use, and with the use of occlusive dressings of

Cream/Ointment: dryness, itching, burning, skin thinning, local irritation, features of hypercortisolism, telangiectasia, striae, skin atrophy. hypertrichosis, change in pigmentation, secondary infection, perioral dermatitis, allergic contact dermatitis, maceration of the skin, acneform eruption, exacerbation of symptoms.

Pregnancy & Lactation

It should not be used extensively in pregnancy

Precautions & Warnings

Betamethasone Cream/Ointment is usually well tolerated but if signs of hypersensitivity appear, the application should be stopped. Long-term continuous topical therapy should be avoided where possible, particularly in children as adrenal suppression may occur even without occlusion. When extensive areas are treated, sufficient systemic absorption may occur to produce symptoms of hypercortisolism. This effect is more likely if occlusive dressings are used, or if the treatment is prolonged. The face or other areas of the body may exhibit atrophic changes after prolonged treatment. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as glaucoma might result. Any spread of the infection requires withdrawal of topical corticosteroid therapy.

Therapeutic Class

Corticosteroid

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Pharmaceutical Name of Betaderm 15 Ointment

Incepta Pharmaceuticals Ltd

Generic of Betaderm 15 Ointment

Betamethasone Valerate