Indications of Bactin 500 Tablet

Ciprofloxacin is demonstrated for the treatment of Respiratory Tract Infections,Urinary tract diseases, Pelvic Fiery Infections, Irresistible The runs (Shigella dysenteriae, Vibrio cholera), Typhoid fever, Intra-abdominal contaminations, Prostatitis, Skin and Delicate Tissue Diseases, Bone and Joint Diseases, Gonorrhea, Neutropenic patients with fever due to bacterial disease, Meningitis, Surgical prophylaxis.

Pharmacology of Bactin 500 Tablet

Ciprofloxacin may be a manufactured fluoroquinolone. It has bactericidal movement against a wide extend of gram-positive and gram-negative living beings. It hinders bacterial DNA blend by official with the bacterial enzyme-DNA gyrase and topoisomerase IV which are capable for DNA supercoiling.

Dosage & Administration of Bactin 500 Tablet

Tablet: Adult:

• Respiratory Tract Infections: 500 to 750 mg twice daily (7 to 14 days)
• Urinary tract infections: 250 to 750 mg twice daily (3 to 10 days)
• Pelvic Inflammatory Diseases: 500 to 750 mg twice daily (14 days)
• Infectious Diarrhea (Shigella dysenteriae, Vibrio cholera): 500 mg twice daily (1 to 5 days)
• Typhoid fever: 500 mg twice daily (7 days)
• Intra-abdominal infections: 500 to 750 mg twice daily (5 to 14 days)
• Prostatitis: 500 to 750 mg twice daily (2 to 6 weeks)
• Skin and Soft Tissue Infections: 500 to 750 mg twice daily (7 to 14 days)
• Bone and Joint Infections: 500 to 750 mg twice daily (max. 3 months)
• Gonorrhea: 500 mg as a single dose
• Neutropenic patients with fever due to bacterial infection: 500 to 750 mg twice daily co-administered with appropriate antibacterials.
• Meningitis: 500 mg as a single dose.
• Surgical prophylaxis: 500 mg as a single dose, 60 minutes before the procedure.

Suspension: Pediatric: 10-20 mg/kg (max. 750 mg) twice daily (10 to 21 days). The duration of therapy depends on the type and severity of the infection.Extended-release tablet: In uncomplicated urinary tract infection (acute cystitis), the recommended dose of extended-release tablet is 1000 mg tablet once daily for three days.

For IV infusion:

• Urinary Tract Infection: Mild to Moderate: 200 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 12 hourly for 7-14 days
• Lower Respiratory Tract infection: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days
• Nosocomial Pneumonia: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days
• Skin and Skin Structure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days
• Bone and Joint Infection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Complicated: 400 mg 8 hourly for more than 4-6weeks
• Intraabdominal (Acute abdomen): Complicated: 400 mg 12 hourly for 7-14 days
• Acute Sinusitis: Mild/Moderate: 400 mg 12 hourly for 10 days
• Chronic Bacterial Prostatitis: Mild/Moderate: 400 mg 12 hourly for 28 Days.

Interaction of Bactin 500 Tablet

Concurrent organization of Ciprofloxacin ought to be maintained a strategic distance from with Magnesium or Aluminum containing stomach settling agents or sucralfate or with other items containing Calcium, Press or Zinc. These items may be taken two hours after or six hours some time recently Ciprofloxacin. Ciprofloxacin ought to not be taken concurrently with drain or other dairy items, since assimilation of Ciprofloxacin may be essentially decreased. Dietary calcium could be a portion of a dinner, be that as it may, does not essentially influence the assimilation of Ciprofloxacin.

Contraindications

It is contraindicated in patients who have known touchiness to Ciprofloxacin or other quinolones.

Side Effects of Bactin 500 Tablet

Side impacts incorporate– sickness and other gastrointestinal unsettling influences, migraine, discombobulation, joint torment and skin rashes.

Pregnancy & Lactation

There are no adequate and well-controlled studies in pregnant women. Ciprofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus and mother. Ciprofloxacin is excreted in human milk. Due to the potential risk of articular damage, Ciprofloxacin should not be used during lactation.

Precautions & Warnings

Patients receiving Ciprofloxacin should be instructed to drink fluids liberally. It should be used with caution in patients with suspected or known CNS disorders such as epilepsy or other factors which predispose to seizures and convulsion. Avoid in patients with known QT prolongation, hypokalemia.

Therapeutic Class

4-Quinolone preparations, Anti-diarrhoeal Antimicrobial drugs

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.

Pharmaceutical Name of Bactin 500 Tablet

Ibn Sina Pharmaceuticals Ltd

Generic of Bactin 500 Tablet

Ciprofloxacin