Artica 100 ML

100110904300101

Artica 100 ML

40.27৳ 

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Description

Generic

Hydroxyzine Hydrochloride

 

Indications

Hydroxyzine Hydrochloride is used to treat the symptoms of anxiety and tension associated with psychoneurosis, as well as to treat anxiety in organic disease conditions.

Pruritus caused by allergic disorders such as chronic urticaria, atopic and contact dermatoses, as well as pruritus caused by histamine.

When administered as a premedication and after general anesthesia, it acts as a sedative.

Hydroxyzine’s efficacy as an antianxiety drug for long-term usage (>4 months) has yet to be determined by comprehensive clinical trials. The drug’s value for the individual patient should be reevaluated on a regular basis by the physician.

 

Pharmacology

Hydroxyzine Hydrochloride is an H1 receptor antagonist and an anxiolytic antihistamine of the piperazine class. Although hydroxyzine is not a cortical depressive, its action may be attributable to a decrease of activity in specific important areas of the central nervous system’s subcortical area. Experimentally, primary skeletal muscle relaxation has been demonstrated. Bronchodilator action, as well as antihistaminic and analgesic properties, have been proven in the lab and verified in the clinic. The antiemetic effect has been established in both the apomorphine and veriloid tests. administration. Hydroxyzine is rapidly absorbed from the gastrointestinal tract and clinical effects are usually noted within 15 to 30 minutes after oral administration.

 

Dosage and Administration

For symptomatic relief of anxiety and tension-

Adults: 50-100 mg 4 times daily.

Children (>6 years): 50-100 mg (5-10 teaspoonfuls) daily in divided doses.

Children (<6 years): 50 mg (5 teaspoonfuls) daily in divided doses.

Pruritus due to allergic conditions-

Adults: 25 mg 3 to 4 times daily.

Children ( 6 years): 50-100 mg (5-10 teaspoonfuls) daily in divided doses.

Children (<6 years): 50 mg (5 teaspoonfuls) daily in divided doses.

As a sedative (premedication and following general anesthesia)-

Adults: 50-100 mg.

Children: 0.6 mg/kg of body weight.

 

Interaction

Hydroxyzine may enhance Meperidine and barbiturates, hence it should be used with caution in pre-anesthetic adjunctive therapy. The medication has no effect on atropine or other belladonna alkaloids. Hydroxyzine is not known to interfere in any manner with the action of digitalis, thus it can be used alongside it. Hydroxyzine should not be taken with monoamine oxidase inhibitors at the same time.

 

Contraindications

Patients who have a known hypersensitivity to Hydroxyzine or any of its constituents should avoid taking it.

 

Side effects

Hydroxyzine Hhydrochloride side effects are often moderate and transient in nature. Drowsiness, headache, psychomotor impairment, and antimuscarinic symptoms such as urine retention, dry mouth, impaired vision, and gastrointestinal problems are the most prevalent adverse effects. Hypotension, palpitation, arrhythmias, extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, hypersensitivity reactions (including bronchospasm, angioedema, and anaphylaxis, rashes, and photosensitivity reactions), blood disorders, liver dysfunction, and angle-closure glaucoma are all rare side effects of antihistamines.

 

Pregnancy & Lactation

Human clinical data is insufficient to show safety in early pregnancy. Hydroxyzine is contraindicated in early pregnancy until more data is available. This medication is not known to be excreted in human milk. Hydroxyzine should not be administered to nursing women because many medicines are eliminated so quickly.

 

Precautions & Warnings

When Hydroxyzine is combined with central nervous system depressants like narcotics, non-narcotic analgesics, and barbiturates, its potentiating effect must be addressed. As a result, when central nervous system depressants are given at the same time as Hydroxyzine, the dosage of the central nervous system depressant should be lowered. Because drowsiness is a possible side effect of Hydroxyzine, patients should be told about it and advised against driving or operating risky machinery while taking it. Patients should be advised against taking other CNS depressants at the same time and warned that the effects of alcohol may be amplified.

 

Therapeutic Class

Sedating Anti-histamine

 

Storage Conditions

Place in a cool, dry location. Protect yourself from the sun. Keep out of children’s reach.

 

Pharmaceutical Name

ACI Limited