Indications
is indicated for the relief of inflammatory and pruritic
manifestations of corticosteroid responsive dermatoses
including atopic dermatitis, contact dermatitis, eczematous
dermatitis, neurodermatitis, seborrheic dermatitis, insect
bites, lichen simplex chronicus, exfoliative dermatitis, stasis
dermatitis, nummular eczema, psoriasis and pruritus ani and
vulvae.
Therapeutic Class
Corticosteroid, Glucocorticoids, Triamcinolone & Combined
preparations
Pharmacology
Triamcinolone Acetonide (a derivative of Triamcinolone) in a
compatible base. Topical steroids are primarily effective
because of their anti-inflammatory, antipruritic &
vasoconstrictive actions.
Dosage & Administration
A small amount of Triamcinolone is gently rubbed on the affected
area 1-2 times daily. Some cases of eczematoid psoriasis
may be treated more effectively by the application of
Triamcinolone under an occlusive dressing.
Occlusive dressing technique: Gently rub a small amount of
Triamcinolone on the lesion until it disappears. Then reapply,
leaving a thin coating, and cover with a pliable nonporous film.
For convenience apply Triamcinolone intermittently (12-hour
occlusion during the night) followed by reapplication without
occlusion, during the day.
Pediatric use: Triamcinolone should not be used in children
under 8 years. Administration of topical corticosteroids to
children should be limited to the least amount compatible
with an effective therapeutic regimen. Chronic corticosteroid
therapy may interfere with the growth and development of
children. As children are more likely to get side effects, they
should not normally be treated for longer than 5 days.
Contraindications
Triamcinolone Acetonide is contraindicated in those patients
with a history of hypersensitivity to any of the components of
the preparation. It is also contraindicated in tuberculosis of
the skin, fungus infections, and viral diseases of the skin
(Herpes simplex, chickenpox, and vaccinia), perioral
dermatitis, rosacea, and ulcerative conditions.
Side Effects
The following local side effects have been reported with
topical corticosteroids, either with or without occlusive
dressings: burning, itching, irritation, dryness, folliculitis,
hypertrichosis, acneiform eruptions, hypopigmentation,
perioral dermatitis and allergic contact dermatitis,
maceration of the skin, secondary infection, skin atrophy,
striae and miliaria.
Pregnancy & Lactation
There are no adequate and well-controlled studies in
pregnant women on teratogenic effects from topically applied
corticosteroids. Therefore, topical corticosteroids should be
used during pregnancy only if the potential benefit justifies
the potential risk to the fetus. It is not known whether topical
administration of corticosteroids could result in sufficient
systemic absorption to produce detectable quantities in
breast milk. Systemically administered corticosteroids are
secreted into breast milk in quantities not likely to have a
deleterious effect on the infant. Nevertheless, caution should
be exercised when topical corticosteroids are administered
to a nursing woman.
Precautions & Warnings
If reactions or idiosyncrasies are encountered, Triamcinolone
Acetonide should be discontinued. The use of topical steroids
on infected areas should be attended to with caution and careful
observation, bearing in mind the potential spreading of
infections by anti-inflammatory steroids and the possible
the advisability of discontinuing steroid therapy and/or initiating
antibacterial measures.
Triamcinolone Acetonide should not be used on healthy skin
or over large areas of skin and not be used in the eye as
there is a potential risk of glaucoma and cataract. When
steroids are applied for long periods of time (more than 4
weeks) the occurrence of atrophic striae is likely. Prolonged
use of flexures and intertriginous areas is undesirable.
Children may absorb proportionately larger amounts of
topical corticosteroids and thus may be more susceptible to
systemic toxicity. In infants, long-term continuous topical
steroid therapy should be avoided. Adrenal suppression can
occur even without occlusion.
Overdose Effects
Topically applied corticosteroids can be absorbed in sufficient
amounts to produce systemic effects e.g., mild, reversible
suppression of adrenal function, ecchymoses of the skin,
peptic ulceration, hypertension, aggravation of infection,
hirsutism, acne, edema, and muscle weakness
Storage Conditions
Store in a cool & dry place. Protect from light.