Indications of Aristo D3 – IM 1ml Injection

Vitamin D3 (Cholecalciferol) helps the body to absorb calcium and phosphorus. It is used to treat and prevent bone disorders (such as rickets, osteomalacia). In combination with calcium, it is used to treat or prevent bone loss (osteoporosis). It is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, and familial hypophosphatemia). It may be used in kidney disease to keep calcium levels normal and allow normal bone growth.

Pharmacology of Aristo D3 – IM 1ml Injection

Cholecalciferol (Vitamin D3) aids in calcium and phosphorus absorption and reabsorption. Vitamin D3 is required for optimal bone growth and density maintenance. It also helps type 2 diabetes patients maintain optimal insulin levels by reducing the severity of bacterial infection, improving lung function, reducing the risk of cancer (breast, colorectal), and preventing cancer (breast, colorectal).

Dosage and Administration of Aristo D3 – IM 1ml Injection

For capsule: Adults:

Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy are 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.

Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations.

Addition to specific therapy for osteoporosis: 20000 IU once a month.

For capsule: Children (12-18 years):

Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks.

Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks.

For film-coated tablets: 1000 IU (1-2 tablets) daily, or as directed by a physician. Take the medicine with food or within 1 hour after a meal.

For flash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by a physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in your mouth and swallow after chewing.

For Syrup:

For patients with a risk of Cholecalciferol deficiency:

0-1 yr: 400 IU/ day (2 ml)

>1 Yr: 600 lU/ day (3 ml)

For Cholecalciferol deficient patients:

0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks

1 -18 yrs: 2000 IU/ day for 6 weeks.

Injection: Prevention:

Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months.

Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months.

Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter.

Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy.

Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular conditions not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months.

Injection: Vitamin D deficiency:

1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.

Interaction of Aristo D3 – IM 1ml Injection

Phenytoin, barbiturates, glucocorticoids, certain laxatives (such as liquid paraffin), actinomycin, and imidazole antifungal medicines are all affected.

Contraindications

Cholecalciferol is contraindicated in all diseases associated with hypercalcemia. It is also contraindicated in patients with known hypersensitivity to Cholecalciferol (or medicines of the same class) and any of the constituent excipients. Cholecalciferol is contraindicated if there is evidence of vitamin D toxicity.

Side Effects of Aristo D3 – IM 1ml Injection

Generally, all nutritional supplements are considered to be safe and well-tolerable. However, few side effects can generally occur including hypercalcemia syndrome or calcium intoxication (depending on the severity and duration of hypercalcemia), occasional acute symptoms include anorexia, headache, nausea, vomiting, abdominal pain or stomach ache, and constipation with the administration of Cholecalciferol.

Pregnancy & Lactation

Use in pregnancy: There is no evidence to suggest that vitamin D3 is teratogenic in humans even at very high doses. Cholecalciferol should be used during pregnancy only if the benefits outweigh the potential risk to the fetus.

Use in nursing mothers: It should be assumed that exogenous Cholecalciferol passes into the breast milk. In view of the potential for hypercalcemia in the mother and for adverse reactions from

Cholecalciferol in nursing infants, mothers may breastfeed while taking Cholecalciferol, provided that the serum Calcium levels of the mother and infant are monitored.

Precautions & Warnings

People with the following conditions should exercise caution when considering taking vitamin D3 supplements:

– High blood calcium or phosphorus level

– Heart problems

– Kidney disease

Vitamin D3 must be taken with adequate amounts of both calcium and magnesium supplementation.

Therapeutic Class

Vitamin in bone formation, Vitamin-D preparations

Storage Conditions

Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children’s reach.

Pharmaceutical Name of Aristo D3 – IM 1ml Injection

Aristopharma Ltd

Generic of Aristo D3 – IM 1ml Injection

Colecalciferol [Vitamin D3]