Acyvir 5GM


Acyvir 5GM


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Indications of Acyvir 5

Acyvir 5 is indicated for the treatment of Herpes simplex keratitis.


Pharmaceutical Name

Aristo vision



Acyvir 5 is a highly active antiviral agent against herpes simplex virus (HSV) types I and II and varicella-zoster in vitro, but it is less toxic to mammalian cells. Acyclovir enters herpes-infected cells and is phosphorylated into the active compound acyclovir triphosphate. The first step of this process requires the presence of virus-encoded thymidine kinase. As an inhibitor and substrate of herpes-specific DNA polymerase, acyclovir triphosphate prevents further viral DNA synthesis without affecting normal cell processes.


Dosage & Administration of Acyvir 5

The dosage for all age groups is the same. A 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac ­five times a day at approximately four hourly intervals. Treatment should continue for at least 3 days after healing



Acyclovir is contraindicated in patients known to be hypersensitive to Acyclovir or Valacyclovir


Side Effects of Acyvir 5

Very common: superficial punctate keratopathy. This does not require early termination of treatment and healing and no obvious sequelae. Common: Slight and transient eye irritation and conjunctivitis appear immediately after use. Rare: Blepharitis.


Pregnancy & Lactation

Pregnancy category B. There are no adequate and well-controlled studies of acyclovir in pregnant women. It is not known whether topical acyclovir will be excreted in human milk.


Precautions & Warnings

The recommended dosage, frequency of applications, and length of treatment should not be exceeded.


Therapeutic Class

Ophthalmic Anti-viral Products


Storage Conditions

Store in a cool and dry place. Keep away from light. Keep out of reach of children. Do not touch the tip of the tube since this may contaminate the product. After one month of the opening do not use the medicine of tube.


Generic Name of Acyvir 5